Wells Fargo Raises Alnylam (ALNY) Revenue Estimates for Amvuttra Despite Projected Margin Compression

1 week ago 7

Maham Fatima

Tue, January 27, 2026 astatine 7:38 AM CST 2 min read

Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY) is 1 of the best US stocks to bargain and clasp successful 2026. On January 20, Wells Fargo adjusted its outlook connected Alnylam Pharmaceuticals, lowering the terms people to $376 from $479 portion maintaining an Equal Weight rating. While the steadfast accrued its 2026 gross estimates for Amvuttra by 6%, it expressed interest implicit rising costs. Specifically, the steadfast expects R&D expenses to ascent to ~30% of full gross betwixt 2026 and 2030. This reinvestment is projected to compress operating margins to astir 30%.

On the aforesaid day, RBC Capital reduced its terms people for Alnylam to $465 from $500 portion maintaining an Outperform rating. This accommodation followed a gathering with the company’s absorption squad to sermon the 2026 nett merchandise gross outlook. Management addressed caller show for Amvuttra, explaining that a brushed November resulted from a fewer one-off factors, which were followed by an awesome December.

Wells Fargo Raises Alnylam (ALNY) Revenue Estimates for Amvuttra Despite Projected Margin Compression

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Earlier connected January 12, Needham accrued its terms people for Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY) from $520 to $529 with a Buy standing pursuing the company’s Q4 2025 pre-announcement and the merchandise of its 2026 fiscal outlook.

Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY) discovers, develops, and commercializes therapeutics based connected ribonucleic acerb interference.

While we admit the imaginable of ALNY arsenic an investment, we judge definite AI stocks connection greater upside imaginable and transportation little downside risk. If you’re looking for an highly undervalued AI banal that besides stands to payment importantly from Trump-era tariffs and the onshoring trend, spot our escaped study connected the best short-term AI stock.

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